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Targeting the Chondroitin Sulfate Proteoglycans: Evaluating Fluorinated Glucosamines and Xylosides in Screens Pertinent to Multiple Sclerosis

[Image: see text] Chondroitin sulfate proteoglycans (CSPGs) are upregulated in insults to the central nervous system, including multiple sclerosis (MS), an inflammatory demyelinating condition of the central nervous system. CSPGs appear to be detrimental in MS, as they enhance immune responses and a...

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Detalles Bibliográficos
Autores principales: Stephenson, Erin L., Zhang, Ping, Ghorbani, Samira, Wang, Aixia, Gu, Jiamin, Keough, Michael B., Rawji, Khalil Sherali, Silva, Claudia, Yong, V. Wee, Ling, Chang-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661872/
https://www.ncbi.nlm.nih.gov/pubmed/31404231
http://dx.doi.org/10.1021/acscentsci.9b00327