NPS2390, a Selective Calcium-sensing Receptor Antagonist Controls the Phenotypic Modulation of Hypoxic Human Pulmonary Arterial Smooth Muscle Cells by Regulating Autophagy

BACKGROUND AND OBJECTIVES: Calcium-sensing receptor (CaSR) is known to regulate hypoxia-induced pulmonary hypertension (HPH) and vascular remodeling via the phenotypic modulation of pulmonary arterial smooth muscle cells (PASMCs) in small pulmonary arteries. Moreover, autophagy is an essential modul...

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Detalles Bibliográficos
Autores principales: Peng, Xue, Wei, Can, Li, Hong-Zhu, Li, Hong-Xia, Bai, Shu-Zhi, Wang, Li-Na, Xi, Yu-Hui, Yan, Jin, Xu, Chang-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661874/
https://www.ncbi.nlm.nih.gov/pubmed/31380238
http://dx.doi.org/10.2478/jtim-2019-0013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661874/
https://www.ncbi.nlm.nih.gov/pubmed/31380238
http://dx.doi.org/10.2478/jtim-2019-0013

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