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Assessment of lipophilicity of newly synthesized celecoxib analogues using reversed-phase HPLC
BACKGROUND: Lipophilicity is a physicochemical property of an essential importance in medicinal chemistry; therefore, fast and reliable measurement of lipophilicity will affect greatly the drug discovery process. RESULTS: A series of N-benzenesulfonamide-1H-pyrazoles, oximes and hydrazones as celeco...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661952/ https://www.ncbi.nlm.nih.gov/pubmed/31384831 http://dx.doi.org/10.1186/s13065-019-0607-6 |