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Neocarzilin A Is a Potent Inhibitor of Cancer Cell Motility Targeting VAT-1 Controlled Pathways

[Image: see text] The natural product neocarzilin A (NCA) was discovered decades ago, and despite its potent cytotoxic effects no mode of action studies have been performed up to date. Synthesis of neocarzilins A, B, and C and a stereoisomer of NCA provided insights into structural preferences as we...

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Detalles Bibliográficos
Autores principales: Gleissner, Carolin M.-L., Pyka, Carolin L., Heydenreuter, Wolfgang, Gronauer, Thomas F., Atzberger, Carina, Korotkov, Vadim S., Cheng, Weiting, Hacker, Stephan M., Vollmar, Angelika M., Braig, Simone, Sieber, Stephan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661975/
https://www.ncbi.nlm.nih.gov/pubmed/31403069
http://dx.doi.org/10.1021/acscentsci.9b00266