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Neocarzilin A Is a Potent Inhibitor of Cancer Cell Motility Targeting VAT-1 Controlled Pathways
[Image: see text] The natural product neocarzilin A (NCA) was discovered decades ago, and despite its potent cytotoxic effects no mode of action studies have been performed up to date. Synthesis of neocarzilins A, B, and C and a stereoisomer of NCA provided insights into structural preferences as we...
Autores principales: | Gleissner, Carolin M.-L., Pyka, Carolin L., Heydenreuter, Wolfgang, Gronauer, Thomas F., Atzberger, Carina, Korotkov, Vadim S., Cheng, Weiting, Hacker, Stephan M., Vollmar, Angelika M., Braig, Simone, Sieber, Stephan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6661975/ https://www.ncbi.nlm.nih.gov/pubmed/31403069 http://dx.doi.org/10.1021/acscentsci.9b00266 |
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