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Determination of Ethinyl Estradiol and Levonorgestrel in Human Plasma with Prednisone as Internal Standard Using Ultra-performance Liquid Chromatography–Tandem Mass Spectrometry

OBJECTIVE: Ethinyl estradiol and levonorgestrel as a combination of oral contraceptive drugs have very low dosage levels; hence, a highly sensitive and selective method of using ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS) is needed. MATERIALS AND METHODS: This metho...

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Detalles Bibliográficos
Autores principales: Harahap, Yahdiana, Devina, Devina, Harmita, Harmita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662037/
https://www.ncbi.nlm.nih.gov/pubmed/31555032
http://dx.doi.org/10.4103/jpbs.JPBS_68_19