Homoarginine Supplementation Prevents Left Ventricular Dilatation and Preserves Systolic Function in a Model of Coronary Artery Disease

BACKGROUND: Homoarginine (hArg) has been shown to be cardioprotective in a model of ischemic heart failure; however, the mechanism remains unknown. hArg can inhibit tissue‐nonspecific alkaline phosphatase (TNAP), an enzyme that promotes vascular calcification. We hypothesized that hArg will exert be...

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Detalles Bibliográficos
Autores principales: Rodionov, Roman N., Begmatov, Hoshimjon, Jarzebska, Natalia, Patel, Ketul, Mills, Matthew T., Ghani, Zulaikha, Khakshour, Doreen, Tamboli, Pankti, Patel, Mitul N., Abdalla, Mirette, Assaf, Maryann, Bornstein, Stefan R., Millan, Jose Luis, Bode‐Böger, Stefanie M., Martens‐Lobenhoffer, Jens, Weiss, Norbert, Savinova, Olga V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662144/
https://www.ncbi.nlm.nih.gov/pubmed/31304837
http://dx.doi.org/10.1161/JAHA.119.012486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662144/
https://www.ncbi.nlm.nih.gov/pubmed/31304837
http://dx.doi.org/10.1161/JAHA.119.012486

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