Cargando…

Homoarginine Supplementation Prevents Left Ventricular Dilatation and Preserves Systolic Function in a Model of Coronary Artery Disease

BACKGROUND: Homoarginine (hArg) has been shown to be cardioprotective in a model of ischemic heart failure; however, the mechanism remains unknown. hArg can inhibit tissue‐nonspecific alkaline phosphatase (TNAP), an enzyme that promotes vascular calcification. We hypothesized that hArg will exert be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodionov, Roman N., Begmatov, Hoshimjon, Jarzebska, Natalia, Patel, Ketul, Mills, Matthew T., Ghani, Zulaikha, Khakshour, Doreen, Tamboli, Pankti, Patel, Mitul N., Abdalla, Mirette, Assaf, Maryann, Bornstein, Stefan R., Millan, Jose Luis, Bode‐Böger, Stefanie M., Martens‐Lobenhoffer, Jens, Weiss, Norbert, Savinova, Olga V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662144/ https://www.ncbi.nlm.nih.gov/pubmed/31304837 http://dx.doi.org/10.1161/JAHA.119.012486

Ejemplares similares

A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2
por: Rodionov, Roman N., et al.
Publicado: (2016)

Homoarginine and methylarginines independently predict long-term outcome in patients presenting with suspicion of venous thromboembolism
por: Rodionov, Roman N., et al.
Publicado: (2021)

Opposite Associations of Plasma Homoarginine and Ornithine with Arginine in Healthy Children and Adolescents
por: JaŸwińska-Kozuba, Aleksandra, et al.
Publicado: (2013)

The Second Life of Methylarginines as Cardiovascular Targets
por: Jarzebska, Natalia, et al.
Publicado: (2019)

Population kinetics of homoarginine and optimized supplementation for cardiovascular risk reduction
por: Kleist, Christine J., et al.
Publicado: (2022)

Low Homoarginine Levels in the Prognosis of Patients With Acute Chest Pain
por: Atzler, Dorothee, et al.
Publicado: (2016)

Developmental dynamics of homoarginine, ADMA and SDMA plasma levels from birth to adolescence
por: Baach, Florence, et al.
Publicado: (2023)

Knock-out of the critical nitric oxide synthase regulator DDAH1 in mice impacts amphetamine sensitivity and dopamine metabolism
por: Kozlova, Alena A., et al.
Publicado: (2023)

Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2
por: Burdin, Dmitry V., et al.
Publicado: (2016)

Low-Circulating Homoarginine is Associated with Dilatation and Decreased Function of the Left Ventricle in the General Population
por: Bahls, Martin, et al.
Publicado: (2018)

Creatine, guanidinoacetate and homoarginine in statin-induced myopathy
por: Neu, Axel, et al.
Publicado: (2020)

Influence of homoarginine on creatine accumulation and biosynthesis in the mouse
por: Lygate, Craig A., et al.
Publicado: (2022)

Lysine and homoarginine are closely interrelated metabolites in the rat
por: Baskal, Svetlana, et al.
Publicado: (2022)

Simultaneous quantification of nirmatrelvir and ritonavir by LC-MS/MS in patients treated for COVID-19
por: Martens-Lobenhoffer, Jens, et al.
Publicado: (2022)

Homoarginine/ADMA ratio and homoarginine/SDMA ratio as independent predictors of cardiovascular mortality and cardiovascular events in lower extremity arterial disease
por: Jud, Philipp, et al.
Publicado: (2018)

Quantification of cGMP in human plasma by isotope dilution LC-MS/MS
por: Martens-Lobenhoffer, Jens, et al.
Publicado: (2009)

Association of Lower Plasma Homoarginine Concentrations with Greater Risk of All-Cause Mortality in the Community: The Framingham Offspring Study
por: Schwedhelm, Edzard, et al.
Publicado: (2020)

Homoarginine Associates with Carotid Intima-Media Thickness and Atrial Fibrillation and Predicts Adverse Events after Stroke
por: Schwieren, Laura, et al.
Publicado: (2023)

Diurnal Variation of L-Arginine and the Cardiovascular Risk Markers Asymmetric and Symmetric Dimethylarginine and Homoarginine in Rotating Night Shift Workers and Controls
por: Hannemann, Juliane, et al.
Publicado: (2023)

Plasma Homoarginine Concentrations According to Use of Hormonal Contraception
por: Helm, Thea, et al.
Publicado: (2018)

l‐Homoarginine supplementation prevents diabetic kidney damage
por: Wetzel, Michael D., et al.
Publicado: (2019)

Cross-Sectional Associations between Homoarginine, Intermediate Phenotypes, and Atrial Fibrillation in the Community—The Gutenberg Health Study
por: Niekamp, Christoph, et al.
Publicado: (2018)

Homoarginine, heart failure, and sudden cardiac death in haemodialysis patients
por: Drechsler, Christiane, et al.
Publicado: (2011)

Homoarginine and Mortality in Pre-Dialysis Chronic Kidney Disease (CKD) Patients
por: Ravani, Pietro, et al.
Publicado: (2013)

Homoarginine and inhibition of human arginase activity: kinetic characterization and biological relevance
por: Tommasi, S., et al.
Publicado: (2018)

Homoarginine ameliorates diabetic nephropathy independent of nitric oxide synthase‐3
por: Wetzel, Michael D., et al.
Publicado: (2021)

Evaluation of the predictive values of elevated serum l-homoarginine and dimethylarginines in preeclampsia
por: Yuan, Xiangmei, et al.
Publicado: (2022)

Homoarginine and creatine deficiency do not exacerbate murine ischaemic heart failure
por: McAndrew, Debra J., et al.
Publicado: (2022)

Overexpression of alanine-glyoxylate aminotransferase 2 protects from asymmetric dimethylarginine-induced endothelial dysfunction and aortic remodeling
por: Rodionov, Roman N., et al.
Publicado: (2022)

Homoarginine—A prognostic indicator in adolescents and adults with complex congenital heart disease?
por: Raedle-Hurst, Tanja, et al.
Publicado: (2017)

Stereochemical Assignment and Absolute Abundance of Nonproteinogenic Amino Acid Homoarginine in Marine Sponges
por: Mohanty, Ipsita, et al.
Publicado: (2021)

The relationship between homoarginine and liver biomarkers: a combination of epidemiological and clinical studies
por: Aghdassi, Ali, et al.
Publicado: (2023)

The biomarker and causal roles of homoarginine in the development of cardiometabolic diseases: an observational and Mendelian randomization analysis
por: Seppälä, Ilkka, et al.
Publicado: (2017)

Cerebrospinal fluid penetration of fosfomycin in patients with ventriculitis: an observational study
por: König, Christina, et al.
Publicado: (2023)

Homoarginine and Progression of Chronic Kidney Disease: Results from the Mild to Moderate Kidney Disease Study
por: Drechsler, Christiane, et al.
Publicado: (2013)

Determination of Homoarginine, Arginine, NMMA, ADMA, and SDMA in Biological Samples by HPLC-ESI-Mass Spectrometry
por: Servillo, Luigi, et al.
Publicado: (2013)

Analysis of L-arginine:glycine amidinotransferase-, creatine- and homoarginine-dependent gene regulation in the murine heart
por: Jensen, Märit, et al.
Publicado: (2020)

Homoarginine- and Creatine-Dependent Gene Regulation in Murine Brains with l-Arginine:Glycine Amidinotransferase Deficiency
por: Jensen, Märit, et al.
Publicado: (2020)

Effects of homoarginine supplementation on heart and skeletal muscle of rats with heart failure with preserved ejection fraction
por: Büttner, Petra, et al.
Publicado: (2022)

Systemic Effects of Homoarginine Supplementation on Arginine Metabolizing Enzymes in Rats with Heart Failure with Preserved Ejection Fraction
por: Büttner, Petra, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rujk362ol93c51s8l7a7alh4n1