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Tanshinones: First-in-Class Inhibitors of the Biogenesis of the Type 3 Secretion System Needle of Pseudomonas aeruginosa for Antibiotic Therapy

[Image: see text] The type 3 secretion system (T3SS) found as cell-surface appendages of many pathogenic Gram-negative bacteria, although nonessential for bacterial survival, is an important therapeutic target for drug discovery and development aimed at inhibiting bacterial virulence without inducin...

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Detalles Bibliográficos
Autores principales: Feng, Chao, Huang, Yinong, He, Wangxiao, Cheng, Xiyao, Liu, Huili, Huang, Yongqi, Ma, Bohan, Zhang, Wei, Liao, Chongbing, Wu, Weihui, Shao, Yongping, Xu, Dan, Su, Zhengding, Lu, Wuyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662154/
https://www.ncbi.nlm.nih.gov/pubmed/31403076
http://dx.doi.org/10.1021/acscentsci.9b00452