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Tumor intrinsic immunity related proteins may be novel tumor suppressors in some types of cancer

Immune checkpoint blockade therapy (ICBT) can unleash T-cell responses against cancer. However, only a small fraction of patients exhibited responses to ICBT. The role of immune checkpoints in cancer cells is not well understood. In this study, we analyzed T-cell coinhibitory/costimulatory genes acr...

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Detalles Bibliográficos
Autores principales: Xiong, Donghai, Wang, Yian, You, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662687/
https://www.ncbi.nlm.nih.gov/pubmed/31358815
http://dx.doi.org/10.1038/s41598-019-47382-3