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In vivo evaluation of the effect of lithium on peripheral circadian clocks by real-time monitoring of clock gene expression in near-freely moving mice

Lithium has been used as a mood stabilizer to treat human bipolar disorders for over half a century. Several studies have suggested the possibility that the efficacy of lithium treatment results in part from the amelioration of circadian dysfunction. However, the effect of lithium on clock gene expr...

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Detalles Bibliográficos
Autores principales: Sawai, Yuka, Okamoto, Takezo, Muranaka, Yugo, Nakamura, Rino, Matsumura, Ritsuko, Node, Koichi, Akashi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662689/
https://www.ncbi.nlm.nih.gov/pubmed/31358797
http://dx.doi.org/10.1038/s41598-019-47053-3