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In vivo evaluation of the effect of lithium on peripheral circadian clocks by real-time monitoring of clock gene expression in near-freely moving mice
Lithium has been used as a mood stabilizer to treat human bipolar disorders for over half a century. Several studies have suggested the possibility that the efficacy of lithium treatment results in part from the amelioration of circadian dysfunction. However, the effect of lithium on clock gene expr...
Autores principales: | Sawai, Yuka, Okamoto, Takezo, Muranaka, Yugo, Nakamura, Rino, Matsumura, Ritsuko, Node, Koichi, Akashi, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662689/ https://www.ncbi.nlm.nih.gov/pubmed/31358797 http://dx.doi.org/10.1038/s41598-019-47053-3 |
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