A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids

Steroidal C19-hydroxylation is pivotal to the synthesis of naturally occurring bioactive C19-OH steroids and 19-norsteroidal pharmaceuticals. However, realizing this transformation is proved to be challenging through either chemical or biological synthesis. Herein, we report a highly efficient metho...

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Detalles Bibliográficos
Autores principales: Wang, Junlin, Zhang, Yanan, Liu, Huanhuan, Shang, Yong, Zhou, Linjun, Wei, Penglin, Yin, Wen-Bing, Deng, Zixin, Qu, Xudong, Zhou, Qianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662754/
https://www.ncbi.nlm.nih.gov/pubmed/31358750
http://dx.doi.org/10.1038/s41467-019-11344-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662754/
https://www.ncbi.nlm.nih.gov/pubmed/31358750
http://dx.doi.org/10.1038/s41467-019-11344-0

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