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Meiosis I progression in spermatogenesis requires a type of testis-specific 20S core proteasome

Spermatogenesis is tightly regulated by ubiquitination and proteasomal degradation, especially during spermiogenesis, in which histones are replaced by protamine. However, the functions of proteasomal activity in meiosis I and II remain elusive. Here, we show that PSMA8-associated proteasomes are es...

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Detalles Bibliográficos
Autores principales: Zhang, Qianting, Ji, Shu-Yan, Busayavalasa, Kiran, Shao, Jingchen, Yu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662770/
https://www.ncbi.nlm.nih.gov/pubmed/31358751
http://dx.doi.org/10.1038/s41467-019-11346-y