Deletion of NFKB1 enhances canonical NF-κB signaling and increases macrophage and myofibroblast content during tendon healing

Flexor tendon injuries heal with excessive scar tissue that limits range of motion and increases incidence of re-rupture. The molecular mechanisms that govern tendon healing are not well defined. Both the canonical nuclear factor kappa B (NF-κB) and mitogen activated protein kinase (MAPK) pathways h...

Descripción completa

Detalles Bibliográficos
Autores principales: Best, Katherine T., Lee, Fredella K., Knapp, Emma, Awad, Hani A., Loiselle, Alayna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662789/
https://www.ncbi.nlm.nih.gov/pubmed/31358843
http://dx.doi.org/10.1038/s41598-019-47461-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662789/
https://www.ncbi.nlm.nih.gov/pubmed/31358843
http://dx.doi.org/10.1038/s41598-019-47461-5

Ejemplares similares