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Deletion of NFKB1 enhances canonical NF-κB signaling and increases macrophage and myofibroblast content during tendon healing
Flexor tendon injuries heal with excessive scar tissue that limits range of motion and increases incidence of re-rupture. The molecular mechanisms that govern tendon healing are not well defined. Both the canonical nuclear factor kappa B (NF-κB) and mitogen activated protein kinase (MAPK) pathways h...
Autores principales: | Best, Katherine T., Lee, Fredella K., Knapp, Emma, Awad, Hani A., Loiselle, Alayna E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662789/ https://www.ncbi.nlm.nih.gov/pubmed/31358843 http://dx.doi.org/10.1038/s41598-019-47461-5 |
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