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Bidirectional optogenetic modulation of prefrontal-hippocampal connectivity in pain-related working memory deficits

Dysfunction of the prefrontal-hippocampal circuit has been identified as a leading cause to pain-related working-memory (WM) deficits. However, the underlying mechanisms remain poorly determined. To address this issue, we implanted multichannel arrays of electrodes in the prelimbic cortex (PL-mPFC),...

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Detalles Bibliográficos
Autores principales: Cardoso-Cruz, Helder, Paiva, Pedro, Monteiro, Clara, Galhardo, Vasco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662802/
https://www.ncbi.nlm.nih.gov/pubmed/31358862
http://dx.doi.org/10.1038/s41598-019-47555-0