A new regulatory mechanism for Raf kinase activation, retinoic acid-bound Crabp1

The rapidly accelerated fibrosarcoma (Raf) kinase is canonically activated by growth factors that regulate multiple cellular processes. In this kinase cascade Raf activation ultimately results in extracellular regulated kinase 1/2 (Erk1/2) activation, which requires Ras binding to the Ras binding do...

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Detalles Bibliográficos
Autores principales: Park, Sung Wook, Nhieu, Jennifer, Persaud, Shawna D., Miller, Michelle C., Xia, Youlin, Lin, Yi-Wei, Lin, Yu-Lung, Kagechika, Hiroyuki, Mayo, Kevin H., Wei, Li-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662813/
https://www.ncbi.nlm.nih.gov/pubmed/31358819
http://dx.doi.org/10.1038/s41598-019-47354-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662813/
https://www.ncbi.nlm.nih.gov/pubmed/31358819
http://dx.doi.org/10.1038/s41598-019-47354-7

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