The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs

The nuclear exosome and its essential co-factor, the RNA helicase MTR4, play crucial roles in several RNA degradation pathways. Besides unwinding RNA substrates for exosome-mediated degradation, MTR4 associates with RNA-binding proteins that function as adaptors in different RNA processing and decay...

Descripción completa

Detalles Bibliográficos
Autores principales: Lingaraju, Mahesh, Johnsen, Dennis, Schlundt, Andreas, Langer, Lukas M., Basquin, Jérôme, Sattler, Michael, Heick Jensen, Torben, Falk, Sebastian, Conti, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662825/
https://www.ncbi.nlm.nih.gov/pubmed/31358741
http://dx.doi.org/10.1038/s41467-019-11339-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662825/
https://www.ncbi.nlm.nih.gov/pubmed/31358741
http://dx.doi.org/10.1038/s41467-019-11339-x

Ejemplares similares