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The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs

The nuclear exosome and its essential co-factor, the RNA helicase MTR4, play crucial roles in several RNA degradation pathways. Besides unwinding RNA substrates for exosome-mediated degradation, MTR4 associates with RNA-binding proteins that function as adaptors in different RNA processing and decay...

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Detalles Bibliográficos
Autores principales:	Lingaraju, Mahesh, Johnsen, Dennis, Schlundt, Andreas, Langer, Lukas M., Basquin, Jérôme, Sattler, Michael, Heick Jensen, Torben, Falk, Sebastian, Conti, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662825/ https://www.ncbi.nlm.nih.gov/pubmed/31358741 http://dx.doi.org/10.1038/s41467-019-11339-x

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