Modifying PTEN recruitment promotes neuron survival, regeneration, and functional recovery after CNS injury

Phosphatase and tensin homolog (PTEN) regulates apoptosis and axonal growth in the developing and adult central nervous system (CNS). Here, we show that human PTEN C-terminal PDZ interactions play a critical role in neuronal apoptosis and axon regeneration after traumatic CNS injury and stroke, high...

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Detalles Bibliográficos
Autores principales: Shabanzadeh, Alireza Pirsaraei, D’Onofrio, Philippe Matteo, Magharious, Mark, Choi, Kyung An Brian, Monnier, Philippe Patrick, Koeberle, Paulo Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662832/
https://www.ncbi.nlm.nih.gov/pubmed/31358730
http://dx.doi.org/10.1038/s41419-019-1802-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662832/
https://www.ncbi.nlm.nih.gov/pubmed/31358730
http://dx.doi.org/10.1038/s41419-019-1802-z

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