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Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors
In recent years, multiple studies including ours have reported on the mechanism of resistance towards valosin-containing protein (VCP) inhibitors. While all these studies reported target alterations via mutations in VCP as the primary mechanism of resistance, discrepancies persist to date regarding...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662852/ https://www.ncbi.nlm.nih.gov/pubmed/31358864 http://dx.doi.org/10.1038/s41598-019-47085-9 |