Cargando…

Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors

In recent years, multiple studies including ours have reported on the mechanism of resistance towards valosin-containing protein (VCP) inhibitors. While all these studies reported target alterations via mutations in VCP as the primary mechanism of resistance, discrepancies persist to date regarding...

Descripción completa

Detalles Bibliográficos
Autores principales: Bastola, Prabhakar, Bilkis, Rabeya, De Souza, Cristabelle, Minn, Kay, Chien, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662852/
https://www.ncbi.nlm.nih.gov/pubmed/31358864
http://dx.doi.org/10.1038/s41598-019-47085-9