Cargando…

Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes

Small RNAs have important functions. However, small RNAs in primate oocytes remain unexplored. Herein, we develop CAS-seq, a single-cell small RNA sequencing method, and profile the small RNAs in human oocytes and embryos. We discover a class of ~20-nt small RNAs that are predominantly expressed in...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Qiyuan, Li, Ronghong, Lyu, Qifeng, Hou, Li, Liu, Zhen, Sun, Qiang, Liu, Miao, Shi, Huijuan, Xu, Beiying, Yin, Mingru, Yan, Zhiguang, Huang, Ying, Liu, Mofang, Li, Yiping, Wu, Ligang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662892/
https://www.ncbi.nlm.nih.gov/pubmed/31358756
http://dx.doi.org/10.1038/s41467-019-11312-8