Cargando…

Prognostic and predictive role of tumour-associated macrophages in HER2 positive breast cancer

Disease outcomes of HER2+ breast cancers have dramatically improved after targeted therapies, such as trastuzumab became available. The main mechanism of action of trastuzumab depends on immunoactivation, while immunosuppressive tumour phenotype has been linked to adverse outcomes. Current study inc...

Descripción completa

Detalles Bibliográficos
Autores principales: Honkanen, Tiia J., Tikkanen, Antti, Karihtala, Peeter, Mäkinen, Markus, Väyrynen, Juha P., Koivunen, Jussi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662906/
https://www.ncbi.nlm.nih.gov/pubmed/31358801
http://dx.doi.org/10.1038/s41598-019-47375-2