m(6)A enhances the phase separation potential of mRNA

N(6)-methyladenosine (m(6)A) is the most prevalent modified nucleotide in mRNA(1,2), with ~25% of mRNAs containing at least one m(6)A. Methylation of mRNA to form m(6)A is required for diverse cellular and physiological processes(3). Although the presence of m(6)A in an mRNA can affect its fate in d...

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Detalles Bibliográficos
Autores principales: Ries, Ryan J., Zaccara, Sara, Klein, Pierre, Olarerin-George, Anthony, Namkoong, Sim, Pickering, Brian F., Patil, Deepak P., Kwak, Hojoong, Lee, Jun Hee, Jaffrey, Samie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662915/
https://www.ncbi.nlm.nih.gov/pubmed/31292544
http://dx.doi.org/10.1038/s41586-019-1374-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662915/
https://www.ncbi.nlm.nih.gov/pubmed/31292544
http://dx.doi.org/10.1038/s41586-019-1374-1

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