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Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish

Tendons are an essential part of the musculoskeletal system, connecting muscle and skeletal elements to enable force generation. The transcription factor scleraxis marks vertebrate tendons from early specification. Scleraxis-null mice are viable and have a range of tendon and bone defects in the tru...

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Detalles Bibliográficos
Autores principales: Kague, Erika, Hughes, Simon M., Lawrence, Elizabeth A., Cross, Stephen, Martin-Silverstone, Elizabeth, Hammond, Chrissy L., Hinits, Yaniv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662971/
https://www.ncbi.nlm.nih.gov/pubmed/31100023
http://dx.doi.org/10.1096/fj.201802654RR