Cargando…

Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish

Tendons are an essential part of the musculoskeletal system, connecting muscle and skeletal elements to enable force generation. The transcription factor scleraxis marks vertebrate tendons from early specification. Scleraxis-null mice are viable and have a range of tendon and bone defects in the tru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kague, Erika, Hughes, Simon M., Lawrence, Elizabeth A., Cross, Stephen, Martin-Silverstone, Elizabeth, Hammond, Chrissy L., Hinits, Yaniv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Federation of American Societies for Experimental Biology 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662971/ https://www.ncbi.nlm.nih.gov/pubmed/31100023 http://dx.doi.org/10.1096/fj.201802654RR

Ejemplares similares

Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system
por: Yoshimoto, Yuki, et al.
Publicado: (2017)

Wnt signalling controls the response to mechanical loading during zebrafish joint development
por: Brunt, Lucy H., et al.
Publicado: (2017)

Wnt16 Elicits a Protective Effect Against Fractures and Supports Bone Repair in Zebrafish
por: McGowan, Lucy M, et al.
Publicado: (2021)

Zebrafish as an Emerging Model for Osteoporosis: A Primary Testing Platform for Screening New Osteo-Active Compounds
por: Bergen, Dylan J. M., et al.
Publicado: (2019)

Dominating lengthscales of zebrafish collective behaviour
por: Yang, Yushi, et al.
Publicado: (2022)

The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function, which leads to early-onset osteoarthritis
por: Lawrence, Elizabeth A., et al.
Publicado: (2018)

Transformed notochordal cells trigger chronic wounds in zebrafish, destabilizing the vertebral column and bone homeostasis
por: López-Cuevas, Paco, et al.
Publicado: (2021)

Development of mandibular, hyoid and hypobranchial muscles in the zebrafish: homologies and evolution of these muscles within bony fishes and tetrapods
por: Diogo, Rui, et al.
Publicado: (2008)

Finite element and deformation analyses predict pattern of bone failure in loaded zebrafish spines
por: Newham, Elis, et al.
Publicado: (2019)

Mef2c factors are required for early but not late addition of cardiomyocytes to the ventricle
por: Kula-Alwar, Duvaraka, et al.
Publicado: (2021)

Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression
por: Stevenson, Nicola L., et al.
Publicado: (2017)

Expression and Function of Scleraxis in the Developing Auditory System
por: Mann, Zoe F., et al.
Publicado: (2013)

Potential of zebrafish as a model to characterise MicroRNA profiles in mechanically mediated joint degeneration
por: Lawrence, Elizabeth A., et al.
Publicado: (2020)

Novel roles for scleraxis in regulating adult tenocyte function
por: Nichols, Anne E. C., et al.
Publicado: (2018)

Scleraxis expressing scleral cells respond to inflammatory stimulation
por: Atta, Ghada, et al.
Publicado: (2021)

Regulation of Cardiac Fibroblast GLS1 Expression by Scleraxis
por: Chattopadhyaya, Sikta, et al.
Publicado: (2022)

Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype
por: Korcari, Antonion, et al.
Publicado: (2023)

3D assessment of intervertebral disc degeneration in zebrafish identifies changes in bone density that prime disc disease
por: Kague, Erika, et al.
Publicado: (2021)

Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis
por: Osborn, Daniel P. S., et al.
Publicado: (2020)

Growth orientations, rather than heterogeneous growth rates, dominate jaw joint morphogenesis in the larval zebrafish
por: Godivier, Josepha, et al.
Publicado: (2022)

The Paratenon Contributes to Scleraxis-Expressing Cells during Patellar Tendon Healing
por: Dyment, Nathaniel A., et al.
Publicado: (2013)

The transcription factor scleraxis is a critical regulator of cardiac fibroblast phenotype
por: Bagchi, Rushita A., et al.
Publicado: (2016)

The Role of Scleraxis in Fate Determination of Mesenchymal Stem Cells for Tenocyte Differentiation
por: Li, Yonghui, et al.
Publicado: (2015)

Defining the spatial-molecular map of fibrotic tendon healing and the drivers of Scleraxis-lineage cell fate and function
por: Ackerman, Jessica E., et al.
Publicado: (2022)

eIF4EBP3L Acts as a Gatekeeper of TORC1 In Activity-Dependent Muscle Growth by Specifically Regulating Mef2ca Translational Initiation
por: Yogev, Orli, et al.
Publicado: (2013)

The Golgi matrix protein giantin is required for normal cilia function in zebrafish
por: Bergen, Dylan J. M., et al.
Publicado: (2017)

Two Dynamin-2 Genes Are Required for Normal Zebrafish Development
por: Gibbs, Elizabeth M., et al.
Publicado: (2013)

Force and scleraxis synergistically promote the commitment of human ES cells derived MSCs to tenocytes
por: Chen, Xiao, et al.
Publicado: (2012)

Retraction Note: The Role of Scleraxis in Fate Determination of Mesenchymal Stem Cells for Tenocyte Differentiation
por: Li, Yonghui, et al.
Publicado: (2018)

Neonatal annulus fibrosus regeneration occurs via recruitment and proliferation of Scleraxis-lineage cells
por: Torre, Olivia M., et al.
Publicado: (2019)

Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis
por: Best, Katherine T, et al.
Publicado: (2021)

Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing
por: Korcari, Antonion, et al.
Publicado: (2022)

Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes
por: Shukunami, Chisa, et al.
Publicado: (2018)

Glutamate signaling through the NMDA receptor reduces the expression of scleraxis in plantaris tendon derived cells
por: Spang, Christoph, et al.
Publicado: (2017)

Distinct functions of alternatively spliced isoforms encoded by zebrafish mef2ca and mef2cb
por: Ganassi, M., et al.
Publicado: (2014)

Skeletogenic Fate of Zebrafish Cranial and Trunk Neural Crest
por: Kague, Erika, et al.
Publicado: (2012)

Zebrafish as a model to study autophagy and its role in skeletal development and disease
por: Moss, Joanna J., et al.
Publicado: (2020)

RNA-Seq Analysis to Identify Novel Roles of Scleraxis during Embryonic Mouse Heart Valve Remodeling
por: Barnette, Damien N., et al.
Publicado: (2014)

Transcription factor scleraxis vitally contributes to progenitor lineage direction in wound healing of adult tendon in mice
por: Sakabe, Tomoya, et al.
Publicado: (2018)

Microbial colonization is required for normal neurobehavioral development in zebrafish
por: Phelps, Drake, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ard468gbvj4f89184tka0qorl0