The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)

BACKGROUND: Apolipoprotein E is a glycoprotein best known as a mediator and regulator of lipid transport and uptake. The APOE-ε4 allele has long been associated with increased risks of Alzheimer's disease and mortality, but the effect of the less prevalent APOE-ε2 allele on diseases in the elde...

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Detalles Bibliográficos
Autores principales: Wolters, Frank J., Yang, Qiong, Biggs, Mary L., Jakobsdottir, Johanna, Li, Shuo, Evans, Daniel S., Bis, Joshua C., Harris, Tamara B., Vasan, Ramachandran S., Zilhao, Nuno R., Ghanbari, Mohsen, Ikram, M. Arfan, Launer, Lenore, Psaty, Bruce M., Tranah, Gregory J., Kulminski, Alexander M., Gudnason, Vilmundur, Seshadri, Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663005/
https://www.ncbi.nlm.nih.gov/pubmed/31356640
http://dx.doi.org/10.1371/journal.pone.0219668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663005/
https://www.ncbi.nlm.nih.gov/pubmed/31356640
http://dx.doi.org/10.1371/journal.pone.0219668

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