Cargando…

Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels

Acid-sensing ion channels have important functions in physiology and pathology, but the molecular composition of acid-activated chloride channels had remained unclear. We now used a genome-wide siRNA screen to molecularly identify the widely expressed acid-sensitive outwardly-rectifying anion channe...

Descripción completa

Detalles Bibliográficos
Autores principales: Ullrich, Florian, Blin, Sandy, Lazarow, Katina, Daubitz, Tony, von Kries, Jens Peter, Jentsch, Thomas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663466/
https://www.ncbi.nlm.nih.gov/pubmed/31318332
http://dx.doi.org/10.7554/eLife.49187