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Identification of TMEM206 proteins as pore of PAORAC/ASOR acid-sensitive chloride channels
Acid-sensing ion channels have important functions in physiology and pathology, but the molecular composition of acid-activated chloride channels had remained unclear. We now used a genome-wide siRNA screen to molecularly identify the widely expressed acid-sensitive outwardly-rectifying anion channe...
Autores principales: | Ullrich, Florian, Blin, Sandy, Lazarow, Katina, Daubitz, Tony, von Kries, Jens Peter, Jentsch, Thomas J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663466/ https://www.ncbi.nlm.nih.gov/pubmed/31318332 http://dx.doi.org/10.7554/eLife.49187 |
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