Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival

Neurofibromatosis type 2 (NF2) is an autosomal-dominant disorder characterized by the development of bilateral vestibular schwannomas. The NF2 gene encodes the tumor suppressor merlin, and loss of merlin activity promotes tumorigenesis and causes NF2. Cellular redox signaling has been implicated in...

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Detalles Bibliográficos
Autores principales: Pestoni, Jeanine C., Klingeman Plati, Stephani, Valdivia Camacho, Oliver D., Fuse, Marisa A., Onatunde, Maria, Sparrow, Nicklaus A., Karajannis, Matthias A., Fernández-Valle, Cristina, Franco, Maria Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663865/
https://www.ncbi.nlm.nih.gov/pubmed/31171721
http://dx.doi.org/10.1074/jbc.RA118.007152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663865/
https://www.ncbi.nlm.nih.gov/pubmed/31171721
http://dx.doi.org/10.1074/jbc.RA118.007152

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