Chrysophanol protects against doxorubicin-induced cardiotoxicity by suppressing cellular PARylation

The clinical application of doxorubicin (DOX) in cancer chemotherapy is limited by its life-threatening cardiotoxic effects. Chrysophanol (CHR), an anthraquinone compound isolated from the rhizome of Rheum palmatum L., is considered to play a broad role in a variety of biological processes. However,...

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Detalles Bibliográficos
Autores principales: Lu, Jing, Li, Jingyan, Hu, Yuehuai, Guo, Zhen, Sun, Duanping, Wang, Panxia, Guo, Kaiteng, Duan, Dayue Darrel, Gao, Si, Jiang, Jianmin, Wang, Junjian, Liu, Peiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663922/
https://www.ncbi.nlm.nih.gov/pubmed/31384538
http://dx.doi.org/10.1016/j.apsb.2018.10.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663922/
https://www.ncbi.nlm.nih.gov/pubmed/31384538
http://dx.doi.org/10.1016/j.apsb.2018.10.008

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