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Targeting the Synapse in Alzheimer’s Disease

Dynamic gain and loss of synapses is fundamental to healthy brain function. While Alzheimer’s Disease (AD) treatment strategies have largely focussed on beta-amyloid and tau protein pathologies, the synapse itself may also be a critical endpoint to consider regarding disease modification. Disruption...

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Detalles Bibliográficos
Autores principales: Jackson, Johanna, Jambrina, Enrique, Li, Jennifer, Marston, Hugh, Menzies, Fiona, Phillips, Keith, Gilmour, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664030/
https://www.ncbi.nlm.nih.gov/pubmed/31396031
http://dx.doi.org/10.3389/fnins.2019.00735