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Novel Gliclazide Electrosprayed Nano-Solid Dispersions: Physicochemical Characterization and Dissolution Evaluation

Purpose: In the current study, electrospraying was directed as a novel alternative approach to improve the physicochemical attributes of gliclazide (GLC), as a poorly water-soluble drug, by creating nanocrystalline/amorphous solid dispersions (ESSs). Methods: ESSs were formulated using Eudragit® RS1...

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Detalles Bibliográficos
Autores principales: Adibkia, Khosro, Ghajar, Solmaz, Osouli-Bostanabad, Karim, Balaei, Niloufar, Emami, Shahram, Barzegar-Jalali, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664122/
https://www.ncbi.nlm.nih.gov/pubmed/31380248
http://dx.doi.org/10.15171/apb.2019.026