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Risperidone Reverses the Downregulation of BDNF in Hippocampal Neurons and MK801-Induced Cognitive Impairment in Rats

MK-801, also known as dizocilpine, is a non-competitive N-methyl-D-aspartic acid (NMDA) receptor antagonist that induces schizophrenia-like symptoms. Our previous study showed that brain-derived neurotrophic factor (BDNF) signaling was upregulated in cultured hippocampal astrocytes in response to MK...

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Detalles Bibliográficos
Autores principales: Yu, Wenjuan, Zhu, Min, Fang, Hongwei, Zhou, Jie, Ye, Le, Bian, Wenyu, Wang, Yuan, Zhu, Hui, Xiao, Jie, Zhu, Hao, Li, Huafang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664152/
https://www.ncbi.nlm.nih.gov/pubmed/31396062
http://dx.doi.org/10.3389/fnbeh.2019.00163