Pathophysiology of Cystic Fibrosis Liver Disease: A Channelopathy Leading to Alterations in Innate Immunity and in Microbiota

Cystic fibrosis (CF) is a monogenic disease caused by mutation of Cftr. CF-associated liver disease (CFLD) is a common nonpulmonary cause of mortality in CF and accounts for approximately 2.5%–5% of overall CF mortality. The peak of the disease is in the pediatric population, but a second wave of li...

Descripción completa

Detalles Bibliográficos
Autores principales: Fiorotto, Romina, Strazzabosco, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664222/
https://www.ncbi.nlm.nih.gov/pubmed/31075352
http://dx.doi.org/10.1016/j.jcmgh.2019.04.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664222/
https://www.ncbi.nlm.nih.gov/pubmed/31075352
http://dx.doi.org/10.1016/j.jcmgh.2019.04.013

Ejemplares similares