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Connecting lysosomes and mitochondria – a novel role for lipid metabolism in cancer cell death

BACKGROUND: The understanding of lysosomes has been expanded in recent research way beyond their view as cellular trash can. Lysosomes are pivotal in regulating metabolism, endocytosis and autophagy and are implicated in cancer. Recently it was discovered that the lysosomal V-ATPase, which is known...

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Detalles Bibliográficos
Autores principales: Bartel, Karin, Pein, Helmut, Popper, Bastian, Schmitt, Sabine, Janaki-Raman, Sudha, Schulze, Almut, Lengauer, Florian, Koeberle, Andreas, Werz, Oliver, Zischka, Hans, Müller, Rolf, Vollmar, Angelika M., von Schwarzenberg, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664539/
https://www.ncbi.nlm.nih.gov/pubmed/31358011
http://dx.doi.org/10.1186/s12964-019-0399-2