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Anti-fibrotic effects of tannic acid through regulation of a sustained TGF-beta receptor signaling

BACKGROUND: Pulmonary fibrosis is a progressive disease characterized by structural distortion of the lungs. Transforming growth factor-beta (TGF-beta) is a key cytokine implicated in the pathogenesis of pulmonary fibrosis. TGF-beta-induced myofibroblast differentiation characterized by expression o...

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Detalles Bibliográficos
Autores principales: Reed, Eleanor B., Ard, Shawn, La, Jennifer, Park, Chan Young, Culligan, Laura, Fredberg, Jeffrey J., Smolyaninova, Larisa V., Orlov, Sergei N., Chen, Bohao, Guzy, Robert, Mutlu, Gökhan M., Dulin, Nickolai O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664561/
https://www.ncbi.nlm.nih.gov/pubmed/31358001
http://dx.doi.org/10.1186/s12931-019-1141-8