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A case of intraplacental gestational choriocarcinoma; characterised by the methylation pattern of the early placenta and an absence of driver mutations

BACKGROUND: Gestational choriocarcinoma is a rare malignancy believed to arise from the trophoblast cells of the placenta. Despite the frequently aggressive clinical nature, choriocarcinoma has been routinely curable with cytotoxic chemotherapy for over 50 years. To date little is known regarding th...

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Detalles Bibliográficos
Autores principales: Savage, Philip, Monk, David, Hernandez Mora, Jose R., van der Westhuizen, Nick, Rauw, Jennifer, Tinker, Anna, Robinson, Wendy, Song, Qianqian, Seckl, Michael J., Fisher, Rosemary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664587/
https://www.ncbi.nlm.nih.gov/pubmed/31357948
http://dx.doi.org/10.1186/s12885-019-5906-8