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Knockdown of estrogen receptor β increases proliferation and affects the transcriptome of endometrial adenocarcinoma cells

BACKGROUND: Estrogen receptor β (ERβ) has been repeatedly suggested to play important roles in hormone-dependent cancer like in tumors of the breast, ovary or prostate. In this study, we intended to further elucidate its role in endometrial cancer. METHODS: For this purpose, we knocked down ERβ expr...

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Detalles Bibliográficos
Autores principales: Treeck, Oliver, Diepolder, Elisabeth, Skrzypczak, Maciej, Schüler-Toprak, Susanne, Ortmann, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664594/
https://www.ncbi.nlm.nih.gov/pubmed/31357971
http://dx.doi.org/10.1186/s12885-019-5928-2