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Mouse embryonic palatal mesenchymal cells maintain stemness through the PTEN-Akt-mTOR autophagic pathway

BACKGROUND: Both genetic and environmental factors are implicated in the pathogenesis of cleft palate. However, the molecular and cellular mechanisms that regulate the development of palatal shelves, which are composed of mesenchymal cells, have not yet been fully elucidated. This study aimed to det...

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Detalles Bibliográficos
Autores principales: Shi, Lungang, Li, Binchen, Zhang, Binna, Zhen, Congyuan, Zhou, Jianda, Tang, Shijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664599/
https://www.ncbi.nlm.nih.gov/pubmed/31358051
http://dx.doi.org/10.1186/s13287-019-1340-8