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LPAR1 regulates the development of intratumoral heterogeneity in ovarian serous cystadenocarcinoma by activating the PI3K/AKT signaling pathway

BACKGROUND: To explore the role of lysophosphatidic acid receptor 1 (LPAR1) and its correlation with the PI3K/AKT pathway in the development of intratumoral heterogeneity (ITH) in human ovarian serous cystadenocarcinoma (OSC). METHODS: Immunohistochemical staining was performed to detect LPAR1 expre...

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Detalles Bibliográficos
Autores principales: Cui, Ran, Cao, Guangming, Bai, Huimin, Zhang, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664705/
https://www.ncbi.nlm.nih.gov/pubmed/31384176
http://dx.doi.org/10.1186/s12935-019-0920-0