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Improving prediction of phenotypic drug response on cancer cell lines using deep convolutional network

BACKGROUND: Understanding the phenotypic drug response on cancer cell lines plays a vital role in anti-cancer drug discovery and re-purposing. The Genomics of Drug Sensitivity in Cancer (GDSC) database provides open data for researchers in phenotypic screening to build and test their models. Previou...

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Detalles Bibliográficos
Autores principales: Liu, Pengfei, Li, Hongjian, Li, Shuai, Leung, Kwong-Sak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664725/
https://www.ncbi.nlm.nih.gov/pubmed/31357929
http://dx.doi.org/10.1186/s12859-019-2910-6