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The role of insulin as a key regulator of seeding, proliferation, and mRNA transcription of human pluripotent stem cells

BACKGROUND: Human-induced pluripotent stem cells (hiPSCs) show a great promise as a renewable source of cells with broad biomedical applications. Since insulin has been used in the maintenance of hiPSCs, in this study we explored the role of insulin in culture of these cells. METHODS: We report cond...

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Detalles Bibliográficos
Autores principales: Shahbazi, Mohammad, Cundiff, Paige, Zhou, Wenyu, Lee, Philip, Patel, Achchhe, D’Souza, Sunita L., Abbasi, Fahim, Quertermous, Thomas, Knowles, Joshua W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664730/
https://www.ncbi.nlm.nih.gov/pubmed/31358052
http://dx.doi.org/10.1186/s13287-019-1319-5