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Frequent genetic aberrations in the cell cycle related genes in mucosal melanoma indicate the potential for targeted therapy

BACKGROUND: Melanoma is one of the most aggressive cancers with extremely poor prognosis, and the median survival time for stage IV patients is approximately 6 to 8 months. Unlike cutaneous melanoma, mucosal melanoma is a rare melanoma subtype among Caucasian patients but its incidence remains as hi...

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Detalles Bibliográficos
Autores principales: Xu, Longwen, Cheng, Zhiyuan, Cui, Chuanliang, Wu, Xiaowen, Yu, Huan, Guo, Jun, Kong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664769/
https://www.ncbi.nlm.nih.gov/pubmed/31358010
http://dx.doi.org/10.1186/s12967-019-1987-z