Cargando…
High temperature suppressed SSC self-renewal through S phase cell cycle arrest but not apoptosis
BACKGROUND: High temperature has a very adverse effect on mammalian spermatogenesis and eventually leads to sub- or infertility through either apoptosis or DNA damage. However, the direct effects of heat stress on the development of spermatogonial stem cells (SSCs) are still unknown because SSCs are...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664773/ https://www.ncbi.nlm.nih.gov/pubmed/31358059 http://dx.doi.org/10.1186/s13287-019-1335-5 |