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Spatial chromatin architecture alteration by structural variations in human genomes at the population scale

BACKGROUND: The number of reported examples of chromatin architecture alterations involved in the regulation of gene transcription and in disease is increasing. However, no genome-wide testing has been performed to assess the abundance of these events and their importance relative to other factors a...

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Detalles Bibliográficos
Autores principales: Sadowski, Michal, Kraft, Agnieszka, Szalaj, Przemyslaw, Wlasnowolski, Michal, Tang, Zhonghui, Ruan, Yijun, Plewczynski, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664780/
https://www.ncbi.nlm.nih.gov/pubmed/31362752
http://dx.doi.org/10.1186/s13059-019-1728-x