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IRESpy: an XGBoost model for prediction of internal ribosome entry sites

BACKGROUND: Internal ribosome entry sites (IRES) are segments of mRNA found in untranslated regions that can recruit the ribosome and initiate translation independently of the 5′ cap-dependent translation initiation mechanism. IRES usually function when 5′ cap-dependent translation initiation has be...

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Detalles Bibliográficos
Autores principales: Wang, Junhui, Gribskov, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664791/
https://www.ncbi.nlm.nih.gov/pubmed/31362694
http://dx.doi.org/10.1186/s12859-019-2999-7