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FoxH1 represses miR-430 during early embryonic development of zebrafish via non-canonical regulation

BACKGROUND: FoxH1 is a forkhead transcription factor with conserved key functions in vertebrate mesoderm induction and left-right patterning downstream of the TGF-beta/Nodal signaling pathway. Binding of the forkhead domain (FHD) of FoxH1 to a highly conserved proximal sequence motif was shown to re...

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Detalles Bibliográficos
Autores principales: Fischer, Patrick, Chen, Hao, Pacho, Frederic, Rieder, Dietmar, Kimmel, Robin A., Meyer, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664792/
https://www.ncbi.nlm.nih.gov/pubmed/31362746
http://dx.doi.org/10.1186/s12915-019-0683-z