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PDX1, a key factor in pancreatic embryogenesis, can exhibit antimetastatic activity in pancreatic ductal adenocarcinoma

Background: In cancer biology, metastasizing is one of the most poorly studied processes. Pancreatic ductal adenocarcinoma (PDAC) is characterized by early metastasis, which is the leading cause of death. The PDX1 protein is crucial for the development of cancer, and its low levels are characteristi...

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Detalles Bibliográficos
Autores principales: Kondratyeva, Liya G, Safina, Dina R, Chernov, Igor P, Kopantzev, Eugene P, Kostrov, Sergey V, Sverdlov, Eugene D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6666369/
https://www.ncbi.nlm.nih.gov/pubmed/31440095
http://dx.doi.org/10.2147/CMAR.S209940